Kish R. Adoni

This study uses single-cell proteomics to show that DNA damage causes heterogeneous and bimodal proteome responses in U2 OS cells, revealing cell-to-cell variability obscured by bulk analysis.

This paper introduces a novel recombinant chymotrypsin (rChymoSelect) with enhanced cleavage specificity, improving proteome coverage and reducing missed cleavages in proteomics workflows.

This paper introduces NanoBondy, a covalent cell-surface modification technology for immune cells using NeissLock chemistry, demonstrating robust and specific ligation to CD45.

This study develops a new mass-spectrometry method to detect protein-glutathionylation, revealing its widespread distribution and dynamic role in regulating protein interactions and active site accessibility across species.

This study shows that both terminal misfolding and polymerisation of Z 1-antitrypsin contribute to liver disease phenotypes, with terminal misfolding driving pro-fibrotic responses and metabolic changes.