Ilan Rosenshine

The paper identifies a mechanism where a small RNA guides a protein regulator to target mRNAs, enabling programmable post-transcriptional control in bacteria.

This study visualizes bacterial nanotube formation in Bacillus subtilis, revealing a novel membranous organelle called the tubeosome that facilitates intercellular communication.

The paper identifies YokF, a nuclease that blocks plasmid transfer via nanotubes in Bacillus subtilis, and shows its homologs in other bacteria restrict NPex.

The paper shows that the plasmid pLS20 uses flagella rotation to trigger conjugation in Gram-positive bacteria, enabling DNA transfer in liquid environments.

The paper identifies EspH's interactions with Rab GTPases and phosphoinositides, showing their roles in immune signaling and membrane trafficking during EPEC infection.

This study shows that activation of the T3SS in EPEC leads to lipid remodeling in the bacterial envelope, increasing antibiotic sensitivity and altering membrane properties.