Mohammed Kaplan

An Expanded Lpt Pathway Couples Surface Lipoprotein Export to Outer Membrane Vesicle Biogenesis in Bacteroides

This study identifies LptZ as a critical protein linking surface lipoprotein export to outer membrane vesicle biogenesis in Bacteroides, revealing a novel pathway and expanding the role of the Lpt machinery.

Bacterial nanotubes extend from a tubeosome organelle to establish an intercellular bridge

This study visualizes bacterial nanotube formation in Bacillus subtilis, revealing a novel membranous organelle called the tubeosome that facilitates intercellular communication.

Diel remodeling and cellular integration of the nitroplast

The paper investigates the cellular integration and diel remodeling of the nitroplast in Braarudosphaera bigelowii, revealing its structural interactions and dynamic membrane changes.

Dual Membrane-spanning Anti-Sigma 2 Controls OMV biogenesis and Colonization Fitness in Bacteroides thetaiotaomicron

This study investigates the role of Dma2 in OMV biogenesis and colonization fitness in Bacteroides thetaiotaomicron, showing that dma2 mutation increases OMV production and affects polysaccharide utilization loci expression, leading to reduced colonization fitness.

Efagins: engineerable agents that evolved independently to target the enterococcal cell wall

The paper identifies efagins, a new class of antibacterial agents that target enterococcal cell wall carbohydrates, and shows they can be engineered for alternative receptor targeting.

In situ architecture of the endosymbiont Wolbachia pipientis

This study uses cryo-electron tomography to reveal the nanoscale architecture of Wolbachia pipientis structures involved in host manipulation and maternal inheritance.

MotorBench: A Cryo-Electron Tomography Dataset of Bacterial Flagellar Motors for Testing Detection Algorithms

The paper introduces MotorBench, a dataset of bacterial flagellar motors for testing automated detection algorithms in cryo-ET.

In situ imaging of bacterial membrane projections and associated protein complexes using electron cryo-tomography

The paper uses electron cryo-tomography to analyze membrane projections and associated protein complexes in bacterial species, identifying diverse structures and protein associations.

Stable sub-complexes observed in situ suggest a modular assembly pathway of the bacterial flagellar motor

The paper observes stable sub-complexes in bacterial flagellar motors using cryo-tomography, suggesting a modular assembly pathway involving independent outer- and inner-membrane sub-complexes.

The structural complexity of the Gammaproteobacteria flagellar motor is related to the type of its torque-generating stators

The paper uses cryo-electron tomography to analyze flagellar motor structures in three Gammaproteobacteria species, finding a correlation between stator type and structural complexity.