Author

René Daer

Arizona State UniversityORCID 0000-0001-7417-1214Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Cassandra M. BarrettiD· 2 shared Karmella Ann HaynesiD· 2 shared Brady Dennison· 1 shared Ernesto Luna MelendeziD· 1 shared Jiaqi Wu· 1 shared Jimmy M. XuiD· 1 shared Ryan Yue MulleriD· 1 shared Stefan J. TekeliD· 1 shared

Activity by Year

2018-2018 · peak 2/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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2 shared papersSynthetic Biology

Cassandra M. BarrettORCID

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2 papers

Recent·Most cited

Synthetic BiologyPLoS ONEPeer-reviewedAug 23, 2018

Characterization of Diverse Homoserine Lactone Synthases in Escherichia coli

René Daer, Cassandra M. Barrett, Ernesto Luna Melendez…·Karmella Ann Haynes

This study characterizes ten homoserine lactone synthases in E. coli, showing their compatibility with the Lux pathway and highlighting disposal risks of HSLs.

16 citations

E. coliexperimental assay

𝕏 PostBluesky

Synthetic BiologybioRxivPreprintMar 11, 2018

Histone modifications and active gene expression are associated with enhanced CRISPR activity in de-silenced chromatin

René Daer, Cassandra M. Barrett, Karmella Ann Haynes

The paper shows that transcriptional activation of silenced chromatin enhances CRISPR activity by reducing histone trimethylation and increasing gene expression.

5 citations

humanCRISPR screen

𝕏 PostBluesky