Cell BiologybioRxivPreprint
A dsRNA Virus Converts Early Endosomes into Stable Replication Organelles Through Maturation Arrest and Retrograde Transport
María Cecilia Giménez, Diego S. Ferrero, Mariam Issa…·Mauricio R. Terebiznik
This study reveals how birnaviruses use VP3 to remodel endosomes into replication compartments through PtdIns(3)P-dependent mechanisms, showing conservation and host adaptation across IBDV and IPNV.
DOI 10.64898/2026.10.02.756243