Author

María Cecilia Giménez

University of TorontoORCID 0009-0006-8038-7242Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Assay:proteomics· 2 Organism:Arabidopsis· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1

Frequent Co-Authors

Mauricio R. TerebiznikiD· 3 shared Serene MoussaouiiD· 3 shared Amanda PaixaoiD· 2 shared Micaela CabriniiD· 2 shared Aaron FountainiD· 1 shared Abdumalik OkhunjonoviD· 1 shared Amir Kanbar· 1 shared Boris HinziD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersCell Biology

Mauricio R. TerebiznikORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Cell BiologybioRxivPreprintOct 6, 2026

A dsRNA Virus Converts Early Endosomes into Stable Replication Organelles Through Maturation Arrest and Retrograde Transport

María Cecilia Giménez, Diego S. Ferrero, Mariam Issa…·Mauricio R. Terebiznik

This study reveals how birnaviruses use VP3 to remodel endosomes into replication compartments through PtdIns(3)P-dependent mechanisms, showing conservation and host adaptation across IBDV and IPNV.

DOI 10.64898/2026.10.02.756243

experimental assay

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Cell BiologybioRxivPreprintSep 17, 2026

3' Plasma Membrane Phosphoinositides Sustain ROS Production at Persistent Non-canonical Phagocytic Cups that Promote Macrophage Control of Aspergillus fumigatus Hyphae

Serene Moussaoui, María Cecilia Giménez, Amanda Paixao…·Mauricio R. Terebiznik

The paper shows macrophages use persistent phagocytic cups to sustain ROS production against A. fumigatus hyphae, overcoming phagocytic size limits through PI(3,4)P2 signaling.

DOI 10.64898/2026.09.14.751521

Arabidopsisproteomics

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Cell BiologyJournal of Cell SciencePeer-reviewedJul 31, 2025

Depletion of endomembrane reservoirs drives phagocytic appetite exhaustion in macrophages

Aaron Fountain, Mélanie Mansat, Tracy Lackraj…·Roberto J. Botelho

This study identifies endomembrane depletion as a key factor in phagocytic capacity exhaustion in macrophages.

8 citations

mouseproteomics

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