Author

Karol Fiedorczuk

Rockefeller UniversityORCID 0000-0001-7439-0222Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

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András SzöllősiiD· 1 shared Csaba MihályiiD· 1 shared I. IordanoviD· 1 shared Jue CheniD· 1 shared László CsanádyiD· 1 shared

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András SzöllősiORCID

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1 paper

Recent·Most cited

BiophysicsProceedings of the National Academy of SciencesPeer-reviewedNov 4, 2024

The structures of protein kinase A in complex with CFTR: mechanisms of phosphorylation and reversible activation

Karol Fiedorczuk, I. Iordanov, Csaba Mihályi…·Jue Chen

This study presents cryo-EM structures of PKA-C bound to CFTR, revealing mechanisms of phosphorylation and reversible activation through catalytic interactions and conformational flexibility.

27 citationstop 2%

humanprotein structure

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