Functional border-associated macrophages limit Alzheimer's Disease progression
Drew I. Adler, Natália Pinheiro-Rosa, Alon Millet, Zoran Z. Gajic, Evan Cheng, Begona Gamallo‐Lana, Yosuke M. Morizawa, Eric Klann, Wen‐Biao Gan, Adam C. Mar, José Henrique Ledo, Hernandez Moura Silva, Juan J. Lafaille
This study shows that border-associated macrophages (BAM) are critical in limiting Alzheimer's Disease progression by clearing beta-amyloid, and their loss accelerates disease pathology.
bioRxiv · Feb 3, 2026 · PreprintImmunology