Hernandez Moura Silva

This study shows that oleic acid reduces NLRP3 inflammasome activity in macrophages, preventing their death and limiting psoriasis-like skin inflammation in mice.

This study shows that border-associated macrophages (BAM) are critical in limiting Alzheimer's Disease progression by clearing beta-amyloid, and their loss accelerates disease pathology.

This paper identifies a CD107a+ macrophage subset with enhanced phagocytic ability for mycobacteria and shows its role in tuberculosis defense.

This study shows mutant p53R172H in pancreatic cancer enhances immunosuppressive chemokine Cxcl1 expression via enhancer activation, reducing immune checkpoint inhibitor efficacy.

The paper analyzes transcriptomic changes in Gli1-deficient neural stem cells during demyelination to identify mechanisms enhancing remyelination.

This study shows that deleting Presenilin 1 in microglia during development enhances memory and neuronal activity in mice, with effects dependent on GluN2B and mitigating Alzheimer's symptoms.