Author

Lucia de Castro

University of Illinois ChicagoORCID 0000-0001-7464-9839Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:Drosophila· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

María Paula ZappiaiD· 2 shared Maxim V. FroloviD· 2 shared Abul Bashar Mir Md. Khademul IslamiD· 1 shared Anton WestacottiD· 1 shared Hannah CookeiD· 1 shared Holly S. JeffersoniD· 1 shared Libby TraversiD· 1 shared Majd ArissiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersDevelopmental Biology

María Paula ZappiaORCID

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2 papers

Recent·Most cited

Developmental BiologybioRxivPreprintFeb 2, 2026

Arginine Kinase 1 regulates energy homeostasis in Drosophila muscle development

María Paula Zappia, Anton Westacott, Hannah Cooke…·Maxim V. Frolov

This study shows that Arginine kinase 1 is essential for energy homeostasis during Drosophila muscle development, affecting myofibrillogenesis, muscle growth, and function.

1 citation

Drosophilabulk RNA-seq

𝕏 PostBluesky

GeneticsEMBO ReportsPeer-reviewedAug 19, 2020

A single-cell transcriptome atlas of the adult muscle precursors uncovers early events in fiber-type divergence in Drosophila

María Paula Zappia, Lucia de Castro, Majd Ariss…·Maxim V. Frolov

The paper constructs a single-cell RNA-seq atlas of Drosophila muscle precursors to identify transcriptional signatures and a novel gene involved in muscle divergence.

38 citations

DrosophilascRNA-seq

𝕏 PostBluesky