Author

Holly S. Jefferson

University College LondonORCID 0000-0002-7989-2317Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:Drosophila· 1 Approach:experimental assay· 1 Assay:metabolomics· 1 Organism:mouse· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Abul Bashar Mir Md. Khademul IslamiD· 1 shared Celine I Brucker· 1 shared Diego Sainz de la MazaiD· 1 shared Lucia de CastroiD· 1 shared Majd ArissiD· 1 shared Marc AmoyeliD· 1 shared María Paula ZappiaiD· 1 shared Maxim V. FroloviD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 16 mutual co-author links

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1 shared paperGenetics

Abul Bashar Mir Md. Khademul IslamORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Somatic cells compartmentalise their metabolism to sustain germ cell survival

Diego Sainz de la Maza, Holly S. Jefferson, Celine I Brucker, Sonia Paoli, Marc Amoyel

The paper shows that somatic gonadal cells in testes break down sugars to produce lactate for germ cell survival, highlighting metabolic compartmentalization as essential for germline maintenance.

The EMBO Journal · Jun 4, 2026Peer-reviewedDevelopmental Biology

A single-cell transcriptome atlas of the adult muscle precursors uncovers early events in fiber-type divergence in Drosophila

María Paula Zappia, Lucia de Castro, Majd Ariss, Holly S. Jefferson, Abul Bashar Mir Md. Khademul Islam, Maxim V. Frolov

The paper constructs a single-cell RNA-seq atlas of Drosophila muscle precursors to identify transcriptional signatures and a novel gene involved in muscle divergence.

EMBO Reports · Aug 19, 2020Peer-reviewedGenetics