Author

Lixuan Wei

Mayo ClinicORCID 0000-0001-7465-7513Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 3 Organism:human· 3 Research Focus:differential expression· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Research Focus:fine-mapping· 1

Frequent Co-Authors

Liewei WangiD· 3 shared Duan LiuiD· 2 shared Huanyao GaoiD· 2 shared Jeong‐Heon LeeiD· 2 shared Richard M. WeinshilboumiD· 2 shared Tamás ÖrdögiD· 2 shared Thanh Thanh L. NguyeniD· 2 shared Zhenqing Ye· 2 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersGenomics

Liewei WangORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

GenomicsNucleic Acids ResearchPeer-reviewedNov 11, 2022

Glucocorticoids Unmask Silent Non-Coding Genetic Risk Variants for Common Diseases

Thanh Thanh L. Nguyen, Huanyao Gao, Duan Liu…·Richard M. Weinshilboum

The paper shows glucocorticoid exposure reveals the function of non-coding genetic variants linked to disease risk by influencing gene expression in relevant biological processes.

11 citations

humanbulk RNA-seq

𝕏 PostBluesky

GenomicsbioRxivPreprintMar 30, 2022

Glucocorticoids Mediate Transcriptome-wide Alternative Polyadenylation: Mechanisms and Functional Implications

Thanh Thanh L. Nguyen, Duan Liu, Huanyao Gao…·Richard M. Weinshilboum

This study shows glucocorticoids regulate alternative polyadenylation in human B-lymphoblastoid cells, affecting gene function and immune-related pathways.

DOI 10.1101/2022.03.30.486468

humanbulk RNA-seq

𝕏 PostBluesky

BioinformaticsbioRxivPreprintJul 6, 2021

A Deep Learning Framework for Prediction of Clinical Drug Response of Cancer Patients and Identification of Drug Sensitivity Biomarkers using Preclinical Samples

David Earl Hostallero, Lixuan Wei, Liewei Wang…·Amin Emad

This paper develops a deep learning framework called TINDL to predict cancer patient drug response and identify drug sensitivity biomarkers using preclinical samples, showing improved performance over other models.

5 citations

humanbulk RNA-seq

𝕏 PostBluesky