Cancer BiologyScience Translational MedicinePeer-reviewed
Personalized Medicine for Meningiomas: Drug Screening on Tumor Organoids Exposes Therapeutic Vulnerabilities to HDAC1/2i Panobinostat
Gerhard Jungwirth, Junguo Cao, Yimin Pan…·Christel C. Herold‐Mende
This study identifies panobinostat as an effective treatment for aggressive meningiomas through drug screening on tumor organoids and reveals a resistance mechanism involving the HDAC8-TGFβ-EMT axis.
6 citationstop 1%