Author

Catharina Lotsch

Heidelberg UniversityORCID 0009-0005-5899-2609Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Andreas von DeimlingiD· 2 shared Christel C. Herold‐MendeiD· 2 shared Felix SahmiD· 2 shared Gerhard JungwirthiD· 2 shared Rolf WartaiD· 2 shared Sandro Manuel KriegiD· 2 shared Alexander YounsiiD· 1 shared Almuth Friederike KessleriD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersCancer Biology

Andreas von DeimlingORCID

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2 papers

Recent·Most cited

Cancer BiologyScience Translational MedicinePeer-reviewedMar 4, 2026

Personalized Medicine for Meningiomas: Drug Screening on Tumor Organoids Exposes Therapeutic Vulnerabilities to HDAC1/2i Panobinostat

Gerhard Jungwirth, Junguo Cao, Yimin Pan…·Christel C. Herold‐Mende

This study identifies panobinostat as an effective treatment for aggressive meningiomas through drug screening on tumor organoids and reveals a resistance mechanism involving the HDAC8-TGFβ-EMT axis.

6 citationstop 1%

humanbulk RNA-seq

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Cancer BiologyActa NeuropathologicaPeer-reviewedOct 9, 2025

Tumor-Associated Macrophages in Meningiomas: An Independent Prognostic Factor for Poor Survival Outperforming the Benefits of T cells

Catharina Lotsch, Rolf Warta, Fang Liu…·Christel C. Herold‐Mende

This study identifies high M2-TAM infiltration as an independent poor survival prognostic factor in meningiomas, overriding the beneficial effect of TILs.

10 citations

humanbulk RNA-seq

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