Christopher J. Westlake

This study identifies key membrane structures and proteins involved in primary ciliogenesis using isotropic ultrastructure imaging and 3D analysis.

This study identifies WDR44 as a driver of de novo α-synuclein aggregation at the lysosomal membrane, linking early aggregation events to neuronal dysfunction in Parkinson's Disease.

This study identifies Kizuna as a regulator of apical microtubule organization during ciliogenesis by interacting with Dvl2 and recruiting PKCδ.

This paper generates a zebrafish model of Alstrom syndrome by knocking out alms1, revealing metabolic defects and beta-cell dysfunction linked to obesity and diabetes.