Author

Carmen C. Leitch

University of Maryland, Baltimore

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:zebrafish· 2 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Norann A. ZaghlouliD· 3 shared Timothy L. Hostelley· 2 shared Adebowale AdeyemoiD· 1 shared Albert G. B. Amoah· 1 shared Amy R. BentleyiD· 1 shared Andrew S. McCallioniD· 1 shared Ayo Priscille DoumateyiD· 1 shared Benjamin EghaniD· 1 shared

Activity by Year

2018-2019 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersGenetics

Norann A. ZaghloulORCID

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Author profile →

3 papers

Recent·Most cited

A Novel Type 2 Diabetes Locus in sub-Saharan Africans, ZRANB3, is Implicated in Beta Cell Proliferation

Adebowale Adeyemo, Guanjie Chen, Ayo Priscille Doumatey, Timothy L. Hostelley, Carmen C. Leitch, Jie Zhou, Amy R. Bentley, Daniel Shriner, Olufemi Adetola Fasanmade, Godfrey Okafor, Benjamin Eghan, Kofi Agyenim‐Boateng, Settara C. Chandrasekharappa, Jokotade Oluremilekun Adeleye, William Balogun, , Charles N. Rotimi

The paper identifies a novel type 2 diabetes locus, ZRANB3, in sub-Saharan Africans and shows its potential role in beta cell proliferation through zebrafish studies.

bioRxiv · May 24, 2019 · PreprintGenetics

Genomic knockout of alms1 in zebrafish recapitulates Alstrom syndrome and provides insight into metabolic phenotypes

Jessica E. Nesmith, Timothy L. Hostelley, Carmen C. Leitch, Maggie S. Matern, Saumil Sethna, Rebecca J. McFarland, Sukanya Lodh, Christopher J. Westlake, Ronna P. Hertzano, Zubair M. Ahmed, Norann A. Zaghloul

This paper generates a zebrafish model of Alstrom syndrome by knocking out alms1, revealing metabolic defects and beta-cell dysfunction linked to obesity and diabetes.

Human Molecular Genetics · Mar 7, 2019Peer-reviewedGenetics

Survey of human chromosome 21 gene expression effects on early development in Danio rerio

Sarah Edie, Norann A. Zaghloul, Carmen C. Leitch, Donna K. Klinedinst, Janette Lebron, Joseph F. Thole, Andrew S. McCallion, Nicholas Katsanis, Roger H. Reeves

The paper screens Hsa21 gene overexpression in zebrafish to study dosage-sensitive effects on early development and identify potential contributors to Down syndrome pathology.

G3 Genes Genomes Genetics · May 14, 2018Peer-reviewedGenetics