Molecular BiologybioRxivPreprint
AT-hook-dependent DNA loop extrusion by STAG1 drives 3D genome folding
Ryota Sakata, Daniel Giménez-Llorente, Ana Losada, Tomoko Nishiyama
This study shows that STAG1's AT-hook motif enhances DNA loop extrusion by cohesin, driving 3D genome folding, while STAG2 lacks this feature.