Author

Ioannis K. Deligiannis

Helmholtz MunichORCID 0000-0001-7498-0804Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1

Frequent Co-Authors

Celia Pilar Martinez‐JimeneziD· 2 shared Anna DaneseiD· 1 shared Catalina A. VallejosiD· 1 shared Dimitris Botskaris· 1 shared E. Lleshi· 1 shared Elena DeligianniiD· 1 shared Haroula Kontaki· 1 shared Iannis TalianidisiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCell Biology

Celia Pilar Martinez‐JimenezORCID

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2 papers

Recent·Most cited

Setdb1 regulates proper differentiation of adult intestinal stem cells via restraining permissive chromatin structure and transcriptional variability

Ioanna Peraki, Liwei Zhang, Dimitris Botskaris, Marianna Stagaki, Ioannis K. Deligiannis, Haroula Kontaki, Elena Deligianni, Ioannis Giannoulakis, Orsalia Georgia Hazapis, Matthieu D. Lavigne, Celia Pilar Martinez‐Jimenez, Iannis Talianidis

This study shows that Setdb1 regulates intestinal stem cell differentiation by controlling chromatin accessibility and transcriptional variability in adult stem cells.

iScience · Jul 9, 2026Peer-reviewedCell Biology

Single-nucleus RNA-seq2 reveals a functional crosstalk between liver zonation and ploidy

Maria Lucia Richter, Ioannis K. Deligiannis, Kelvin Yin, Anna Danese, E. Lleshi, Paul G. Coupland, Catalina A. Vallejos, Kylie P. Matchett, Neil Cowan Henderson, Maria Colomé‐Tatché, Celia Pilar Martinez‐Jimenez

The paper develops a single-nucleus RNA-seq2 method to study ploidy and spatial zonation in hepatocytes, finding gene expression in tetraploid cells depends on their hepatic lobe position.

Nature Communications · Jul 12, 2021Peer-reviewedGenomics