Author

Riley K. Togashi

Stanford MedicineORCID 0000-0001-7499-3189Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

Athina Zerva· 2 shared James CheniD· 2 shared Martin P. SchwalmiD· 2 shared Nicolai D. RaigiD· 2 shared Stefan KnappiD· 2 shared Thomas HankeiD· 2 shared Zaile ZhuangiD· 2 shared Andreas Kraemer· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersBiochemistry

Athina Zerva

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2 papers

Recent·Most cited

BiochemistryJournal of the American Chemical SocietyPeer-reviewedOct 5, 2026

Small-molecule modulators of HIPK4 activity and proteostasis

Zaile Zhuang, Riley K. Togashi, Patrick C. Kearney…·James Chen

This study identifies cyanoquinoline-based HIPK4 inhibitors with nanomolar potency and reveals their cell-type-specific effects on HIPK4 proteostasis and autophagy.

DOI 10.1021/jacs.6c10097

mouseproteomics

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BiochemistryJournal of Medicinal ChemistryPeer-reviewedAug 18, 2026

Macrocyclization of Broad-Spectrum Kinase Inhibitor Bosutinib leads to Potent and Selective Quinoline-based HIPK4 Inhibitor AZ137

Athina Zerva, Nicolai D. Raig, Zaile Zhuang…·Thomas Hanke

The paper describes the development of AZ137, a potent and selective HIPK4 inhibitor derived from bosutinib, and validates its utility as a tool for studying HIPK4's biological functions.

1 citation

experimental assaydrug response / drug discovery

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