Xiaoqin Sun

Seq2Neo predicts neoantigen immunogenicity using a CNN model trained on genomic alterations, outperforming existing tools in independent datasets.

This study shows that Ggct deletion in mice causes splenomegaly and anemia due to oxidative damage and reduced glutathione in red blood cells.

This paper critiques a previous study that claimed no neoantigen depletion signal in untreated cancer genomes, arguing that the study's methodology is flawed due to misalignment between defined HLA-binding regions and actual immunogenic neoantigens.