Wonmuk Hwang

The paper analyzes the evolution of correlated conformational dynamics in influenza A virus NS1 proteins, revealing a core-periphery structure that enables evolutionary sequence variation while maintaining structural robustness.

The paper identifies how TCR-ligand interactions influence memory T-cell differentiation by analyzing clonotype-specific signaling and functional outcomes.

The paper compares the mechanical behavior of two TCRs recognizing the same pMHC using MD simulations, showing differences in load response due to dynamic allostery.

This study analyzes how mutations in the NS1 protein of influenza A virus rewired allosteric and epistatic networks, enhancing its binding affinity to p85β.