Author
Dana-Farber Cancer InstituteORCID 0000-0002-2087-9468Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Aoi Akitsu, Kemin Tan, Robert J. Mallis…·Ellis L. Reinherz
The paper identifies how TCR-ligand interactions influence memory T-cell differentiation by analyzing clonotype-specific signaling and functional outcomes.
Koji Haratani, Bruce B. Reinhold, Jonathan S. Duke‐Cohan…·Ellis L. Reinherz
This study identifies that cancers limit p53 neoantigen display on MHC molecules, evading T cell detection through immune selection and ERAP1-mediated destruction.
Ana Cristina Chang-Gonzalez, Aoi Akitsu, Robert J. Mallis…·Wonmuk Hwang
The paper compares the mechanical behavior of two TCRs recognizing the same pMHC using MD simulations, showing differences in load response due to dynamic allostery.