Author

Irina Linkov

Memorial Sloan Kettering Cancer CenterORCID 0000-0001-7520-5359Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Achim A. JungbluthiD· 1 shared Afşar BarlasiD· 1 shared Aleksandar ObradovićiD· 1 shared Alister P. W. FunnelliD· 1 shared Àlvaro Quintanal-VillalongaiD· 1 shared Andrea ArfèiD· 1 shared Anuradha GopalaniD· 1 shared Arielle ElkriefiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

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10 top collaborators · 20 mutual co-author links

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1 shared paperCancer Biology

Achim A. JungbluthORCID

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2 papers

Recent·Most cited

Cancer BiologyTranslational OncologyPeer-reviewedJul 20, 2026

SMARCA4, STK11, and KEAP1 co-inactivation associates with poor prognosis and upregulation of the TGF-β pathway in lung adenocarcinoma

Emily A. Costa, Barbara Vaz de Mello, Corrin A. Wohlhieter…·Charles M. Rudin

The paper identifies SMARCA4/STK11/KEAP1 triple mutant lung adenocarcinoma as a poor prognosis subset and links it to TGF-β pathway activation.

DOI 10.1016/j.tranon.2026.102915

humanbulk RNA-seq

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Cancer BiologyProceedings of the National Academy of SciencesPeer-reviewedJul 5, 2024

Single Cell Analysis of Treatment-Resistant Prostate Cancer: Implications of Cell State Changes for Cell Surface Antigen Targeted Therapies

Samir Zaidi, Jooyoung Park, Joseph Minhow Chan…·Charles L. Sawyers

The paper uses single-cell analysis to study how cell surface antigen expression changes in treatment-resistant prostate cancer, revealing transcriptional heterogeneity and shared gene regulatory networks between NEPC and SCLC.

73 citationstop 1%

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