Yuichi Wakana

The paper shows extracellular mechanical forces influence Golgi secretory function by modulating carrier biogenesis and exocytosis, with molecular determinants including microtubule acetylation and protein kinase D activity.

The paper identifies a PKD-caveolin mechanism for TGN carrier biogenesis, linking lipid transfer and cargo sorting to membrane remodeling.

This study shows Legionella pneumophila transforms the host ER membrane into a distinct rER niche using Rab GTPases and BAP31.