Anabel‐Lise Le Roux

Amphipathic helices sense the inner nuclear membrane environment through lipid packing defects

The paper identifies how amphipathic helices bind to the inner nuclear membrane by sensing lipid packing defects rather than electrostatics, showing the INM's loose packing under basal conditions.

Mechanical forces stimulate Golgi export

The paper shows extracellular mechanical forces influence Golgi secretory function by modulating carrier biogenesis and exocytosis, with molecular determinants including microtubule acetylation and protein kinase D activity.

Lipid-driven SRC self-association modulates its transformation capacity

The paper shows lipid-mediated self-association of Src kinase forms condensates on lipid bilayers, modulating its transforming capacity through a lysine cluster in the SH4 domain.