Iaroslav Popov

The paper introduces WxS-QC, a quality control pipeline for human WGS and WES data, and provides an open test dataset to evaluate QC methods.

The paper performs whole exome sequencing on 44,028 British South Asians to identify gene-phenotype associations and knockout genes, finding novel links and implications for drug development.

This pilot study identifies British South Asians at high risk of cholestatic liver disease through genetic and phenotypic recall, finding 66.7% of participants had undetected liver disease.

This study estimates that ~6% of insulin-treated diabetic individuals with ambiguous features in British Pakistanis and Bangladeshis have T1D, highlighting the need for autoantibody and C-peptide testing.

The paper analyzes allele and haplotype frequencies of GC gene polymorphisms in Eurasian populations to explore their association with vitamin D levels and potential adaptation to solar insolation.

This study conducts a GWAS on alcohol consumption in a Russian population, finding no genome-wide significant SNPs but identifying associations with genes related to nervous system function and mental disorders.

The paper identifies novel autoregulatory feedback loops where RNA-binding proteins regulate their own expression via alternative splicing and nonsense-mediated mRNA decay.