MicrobiologyInfection and ImmunityPeer-reviewed
Cross-species protection suggests Entamoeba histolytica trogocytosis enables complement resistance through the transfer of negative regulators of complement activation
Maura C. Ruyechan, Wesley Huang, Katherine S. Ralston
The paper shows that Entamoeba histolytica uses trogocytosis to acquire and display human complement regulators, enabling resistance to complement lysis even when exposed to mouse serum.
DOI 10.1128/iai.00220-25