Author

Samir Sayem El-Dahr

Tulane UniversityORCID 0000-0001-7571-4292Unclaimed ORCID profile · follow to get notified of new preprints

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Approach:statistical model· 4 Research Focus:gene regulatory network inference· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:scRNA-seq· 2 Assay:ATAC-seq· 1 Approach:experimental assay· 1

Frequent Co-Authors

Giovane G. TorteloteiD· 2 shared Hongbing LiuiD· 2 shared Jay K. KollsiD· 2 shared Alanna G. Wanek· 1 shared Andrew KeniryiD· 1 shared Ashley Spencer· 1 shared Chao-Hui Chen· 1 shared Chao‐Hui Chen· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersDevelopmental Biology

Giovane G. TorteloteORCID

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4 papers

Recent·Most cited

The molecular and cellular anatomy of a fetal programming defect: the impact of low protein diet on the developing kidney.

Kieran M. Short, Giovane G. Tortelote, Lynelle K. Jones, Fabiola Diniz, Francesca Edgington-Giordano, Luise A. Cullen‐McEwen, Jan Schröder, Ashley Spencer, Andrew Keniry, Jose Maria Polo, John F. Bertram, Marnie E. Blewitt, Ian Smyth, Samir Sayem El-Dahr

This study investigates how a maternal low protein diet affects kidney development in mice, revealing molecular and cellular changes that reduce nephron number.

Journal of the American Society of Nephrology · Mar 26, 2026Peer-reviewedDevelopmental Biology

Single cell regulatory architecture of human pancreatic islets suggests sex differences in β cell function and the pathogenesis of type 2 diabetes.

Mirza Muhammad Fahd Qadir, Ruth M. Elgamal, Kejing Song, Parul Kudtarkar, Siva S. V. P. Sakamuri, Prasad V. G. Katakam, Samir Sayem El-Dahr, Jay K. Kolls, Kyle J. Gaulton, Franck Mauvais‐Jarvis

The paper examines sex and race differences in human pancreatic islets using scRNA-seq and snATAC-seq, finding sex-specific gene expression and chromatin accessibility differences in β cells that change with type 2 diabetes.

The EMBO Journal · Nov 20, 2024Peer-reviewedGenomics

Single-cell chromatin and gene-regulatory dynamics of mouse nephron progenitors

Sylvia Hilliard, Giovane G. Tortelote, Hongbing Liu, Chao-Hui Chen, Samir S. El-Dahr

The paper uses single-cell chromatin accessibility and gene expression data to study regulatory dynamics in mouse nephron progenitors, identifying cell-type-specific cis-regulatory elements and transcription factors involved in fate decisions.

Journal of the American Society of Nephrology · Apr 5, 2022Peer-reviewedDevelopmental Biology

Defining the dynamic chromatin landscape of nephron progenitors

Sylvia A. Hilliard, Renfang Song, Hongbing Liu, Chao‐Hui Chen, Yuwen Li, Melody Baddoo, Erik F. Flemington, Alanna G. Wanek, Jay K. Kolls, Zubaida R. Saifudeen, Samir Sayem El-Dahr

The paper examines the chromatin landscape of nephron progenitors across age, identifying age-related changes in chromatin accessibility and regulatory regions that suggest old progenitors are epigenetically primed for differentiation.

Biology Open · Jan 1, 2019Peer-reviewedDevelopmental Biology