Author

Simona Saccani

Centre National de la Recherche ScientifiqueORCID 0000-0001-7572-3308Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Dominic van EsseniD· 2 shared Adina AukenovaiD· 1 shared Arpita SarkariD· 1 shared Aurélien J. DoucetiD· 1 shared Beate HeizmanniD· 1 shared Cécilia Domrane· 1 shared Céline CharvetiD· 1 shared Claude Philippe· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersImmunology

Dominic van EssenORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintJun 9, 2025

How Ikaros and Aiolos homo- and heterodimers drive gene expression to ensure B cell development

Marie‐Céline Deau, Beate Heizmann, Adina Aukenova…·Susan H. Chan

This study identifies the distinct roles of Ikaros and Aiolos homo- and heterodimers in B cell development, showing they regulate different gene sets and functions through varied transcriptional mechanisms.

DOI 10.1101/2025.06.09.658591

mouseChIP-seq

GenomicsCell GenomicsPeer-reviewedFeb 1, 2024

Comprehensive locus-specific L1 DNA methylation profiling reveals the epigenetic and transcriptional interplay between L1s and their integration sites.

Sophie Lanciano, Claude Philippe, Arpita Sarkar…·Gaël Cristofari

The paper profiles L1 DNA methylation at single-locus resolution across normal and cancer cells, revealing how methylation and transcription interact with L1 integration sites.

50 citationstop 2%

humanwhole-genome sequencing