Author

Claude Philippe

Centre National de la Recherche Scientifique

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Organism:mouse· 1

Frequent Co-Authors

Gaël CristofariiD· 3 shared Adam D. EwingiD· 1 shared Alejandro Rubio-RoldániD· 1 shared Ángela MaciaiD· 1 shared Antonio Gómez‐MartíniD· 1 shared Arpita SarkariD· 1 shared Aurélien J. DoucetiD· 1 shared Beatriz González-AlzagaiD· 1 shared

Activity by Year

2019-2024 · peak 1/yr

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10 top collaborators · 27 mutual co-author links

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3 shared papersGenomics

Gaël CristofariORCID

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3 papers

Recent·Most cited

Comprehensive locus-specific L1 DNA methylation profiling reveals the epigenetic and transcriptional interplay between L1s and their integration sites.

Sophie Lanciano, Claude Philippe, Arpita Sarkar, David Pratella, Cécilia Domrane, Aurélien J. Doucet, Dominic van Essen, Simona Saccani, Laure Ferry, Pierre‐Antoine Defossez, Gaël Cristofari

The paper profiles L1 DNA methylation at single-locus resolution across normal and cancer cells, revealing how methylation and transcription interact with L1 integration sites.

Cell Genomics · Feb 1, 2024Peer-reviewedGenomics

Locus-specific chromatin profiling of evolutionarily young transposable elements

Darren Taylor, Robert Lowe, Claude Philippe, Kevin C L Cheng, Olivia A. Grant, Nicolae Radu Zabet, Gaël Cristofari, Miguel Ramos Branco

The paper develops a method to generate locus-specific chromatin profiles at transposable elements using HiChIP and PAtChER, revealing epigenetic variation in young TEs in mouse and human cells.

Nucleic Acids Research · Dec 2, 2021Peer-reviewedGenomics

LINE-1 retrotransposition impacts the genome of human pre implantation embryos and extraembryonic tissues

Martín Muñoz-López, Raquel Vilar, Claude Philippe, Raheleh Rahbari, Sandra R. Richardson, Miguel Andrés-Antón, Thomas J. Widmann, David Cano, José Luis Cortés, Alejandro Rubio-Roldán, Etienne Guichard, Sara R. Heras, Francisco Jose Sanchez-Luque, Maria H. Morell, Elisabet Aguilar, , Jose Luis Garcia-Perez

This study shows LINE-1 retrotransposition occurs in human pre-implantation embryos and extraembryonic tissues, impacting gene expression and potentially contributing to genomic variation.

bioRxiv · Jan 18, 2019 · PreprintGenomics