Ambra Dondi

The paper shows that the duration of DNA damage checkpoint arrest in budding yeast predicts post-mitotic proliferative competence after checkpoint adaptation.

This study identifies a mechanism by which Cdc5 and Cdc14 coordinate to resolve DNA catenanes through regulation of Topoisomerase II during mitosis.

This study shows that NF1 loss increases sensitivity to the ADC T-DM1 by modulating microtubule repair and dynamics, identifying NF1 as a predictive biomarker for ADC response.