Author

Andrea Polazzi

European Institute of OncologyORCID 0000-0001-5642-5882Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Alejo Rodriguez-FraticelliiD· 1 shared Alessia Castiglioni· 1 shared Alessia Farfalla· 1 shared Alex Maya Pombo· 1 shared Ambra DondiiD· 1 shared Andrew Davis· 1 shared Arielle J. MedfordiD· 1 shared Bruno Achutti DusoiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

Alejo Rodriguez-FraticelliORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintFeb 25, 2026

Leukemia stem cell expansion cultures reveal clonal drivers of leukemogenesis and therapy response

Indranil Singh, Andrea Polazzi, Alex Maya Pombo…·Alejo Rodriguez-Fraticelli

This paper develops PLSTCs to expand AML LSCs and identifies clonal drivers of leukemogenesis and therapy response through genomic and single-cell analyses.

1 citation

humanscRNA-seq

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Cancer BiologybioRxivPreprintDec 6, 2023

NF1 modulates microtubule repair and sensitivity to antibody-drug conjugates

Bruno Achutti Duso, Eleonora Messuti, Giulia Tini…·Luca Mazzarella

This study shows that NF1 loss increases sensitivity to the ADC T-DM1 by modulating microtubule repair and dynamics, identifying NF1 as a predictive biomarker for ADC response.

1 citation

humanproteomics

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