Kimberly D. Siegmund

This paper introduces an annotation-based gene-peak linkage method that improves gene expression prediction from chromatin accessibility in human kidney multi-omics data.

The paper shows that epigenetic conservation of genes correlates with their functional importance in human cells and drug sensitivity.

The paper quantifies individual and sex differences in structural brain development from childhood to young adulthood using MRI data from three longitudinal datasets.

HiLDA identifies mutational patterns and their frequencies in cancer data, showing significant associations with mutation timing in colon cancer.