Author

Ellen Goossens

Vrije Universiteit BrusselORCID 0000-0001-7601-9689Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Anders JuuliD· 1 shared Camille RaetsiD· 1 shared Emily DelgouffeiD· 1 shared Ewa Rajpert‐De MeytsiD· 1 shared Frédéric ChalmeliD· 1 shared Gülizar SaritaşiD· 1 shared Guy G. T'SjoeniD· 1 shared Inge GiesiD· 1 shared

Activity by Year

2024-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperGenetics

Anders JuulORCID

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3 papers

Recent·Most cited

GeneticsHuman ReproductionPeer-reviewedAug 9, 2024

Testicular mosaicism in non-mosaic postpubertal Klinefelter patients with focal spermatogenesis and in non-mosaic prepubertal Klinefelter boys

Semir Gül, Veerle Vloeberghs, Inge Gies, Ellen Goossens

The paper investigates testicular mosaicism in non-mosaic Klinefelter Syndrome patients, finding that spermatogonia are euploid while surrounding Sertoli cells show karyotype differences between prepubertal and postpubertal stages.

5 citations

humanstatistical model

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GeneticsCell Death and DiseasePeer-reviewedJun 5, 2024

X-chromosome loss rescues Sertoli cell maturation and spermatogenesis in Klinefelter syndrome

Sofia Boeg Winge, Niels Erik Skakkebæk, Lise Aksglæde…·Kristian Almstrup

The paper shows that X-chromosome loss in Sertoli cells enables maturation and focal spermatogenesis in Klinefelter syndrome.

12 citations

human

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Developmental BiologybioRxivJan 25, 2024

Partial rejuvenation of the spermatogonial stem cell niche after gender-affirming hormone therapy in trans women

Emily Delgouffe, Samuel Madureira Silva, Frédéric Chalmel…·Ellen Goossens

This study examines how gender-affirming hormone therapy affects the spermatogonial stem cell niche in trans women, finding partial rejuvenation of somatic cells and fibrotic changes.

3 citations

humanbulk RNA-seq

𝕏 PostBluesky