CATSPERϵ extracellular domains are essential for sperm calcium channel assembly and activity modulation
Jae Yeon Hwang, Huafeng Wang, Jong‐Nam Oh, Jingon Kim, Sarah F Finnegan, Niels Erik Skakkebæk, Jean‐Ju Chung
This study identifies the essential role of CATSPERε extracellular domains in assembling the CatSper channel complex and modulating sperm hyperactivation and fertilization.
Science Advances · Jan 28, 2026Peer-reviewedCell Biology