Yan Li

This study develops a humanized SLE model to compare B cell-targeted therapies, finding UCAR-T provides better renal and autoantibody reduction than TCEs despite higher toxicity.

The paper identifies human myelocyte and metamyelocyte-stage neutrophils as immunosuppressive cells that promote cancer progression and suggests targeting them for immunotherapy.

The paper investigates how a polymorphism in a RUNX3 enhancer affects TF binding in CD8+ T-cells, linking it to ankylosing spondylitis risk.