Author

Stefan Alexander Przyborski

Durham UniversityORCID 0000-0001-7613-525XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Molecular Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Adriana BuskiniD· 1 shared Ai Ling SooniD· 1 shared Alastair DroopiD· 1 shared Alexa B. KimballiD· 1 shared Basudha BasuiD· 1 shared Bradley B. JarroldiD· 1 shared Calvin Nguyen· 1 shared Carla MelloughiD· 1 shared

Activity by Year

2017-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperGenetics

Adriana BuskinORCID

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3 papers

Recent·Most cited

Molecular BiologybioRxivPreprintAug 15, 2022

Cell Senescence-Independent Ageing of Human Skin

James Wordsworth, Nicola Fullard, Claire E. Welsh…·Daryl P. Shanley

The paper shows that while senescent cells contribute to collagen degradation with age, reduced collagen production in adult skin is due to senescence-independent processes.

2 citations

humanbulk RNA-seq

𝕏 PostBluesky

Systems BiologyExperimental DermatologyPeer-reviewedAug 2, 2022

Inflammaging in human photoexposed skin: Early onset of senescence and imbalanced epidermal homeostasis across the decades.

Bradley B. Jarrold, Christina Yan Ru Tan, Chin Yee Ho…·John E. Oblong

The paper investigates inflammaging in human photoexposed skin, identifying early senescence and imbalanced epidermal homeostasis across age groups.

27 citationstop 3%

humanbulk RNA-seq

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GeneticsbioRxivPreprintDec 11, 2017

Human iPSC-derived RPE and retinal organoids reveal impaired alternative splicing of genes involved in pre-mRNA splicing in PRPF31 autosomal dominant retinitis pigmentosa

Adriana Buskin, Lili Zhu, Valeria Chichagova…·Majlinda Lako

The paper generates patient-specific retinal organoids and RPE from RP type 11 patients to show PRPF31 mutations cause retinal-specific splicing defects and structural/functional impairments, which are corrected by in situ gene editing.

5 citations

humanscRNA-seq

𝕏 PostBluesky