Isabela Corina Fortunato

This paper develops a minimal physical model to explain haptotaxis and oscillatory cell migration by linking adhesion strength to protrusive actin activity.

This study shows cells exhibit complex migration patterns along haptotactic gradients, including oscillations and directed movement, and develops a biophysical model to explain these behaviors.

The paper shows that competition between biochemical and mechanical cues regulates endothelial cell polarity, driving vascular morphogenesis through tension shifts.