Author

Mauro Delorenzi

SIB Swiss Institute of BioinformaticsORCID 0000-0001-7631-3263Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2

Frequent Co-Authors

Annika KelleriD· 2 shared Johanna SchaffenrathiD· 2 shared Melanie GreteriD· 2 shared Sina NassiriiD· 2 shared Sucheta SridhariD· 2 shared Upasana MaheshwariiD· 2 shared Adriano AguzziiD· 1 shared Ana AmorimiD· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersNeuroscience

Annika KellerORCID

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2 papers

Recent·Most cited

Pericytes regulate vascular immune homeostasis in the CNS

Orsolya Török, Bettina Schreiner, Johanna Schaffenrath, Hsing‐Chuan Tsai, Upasana Maheshwari, Sebastian A. Stifter, Christina A. Welsh, Ana Amorim, Sucheta Sridhar, Sebastian G. Utz, Wiebke Mildenberger, Sina Nassiri, Mauro Delorenzi, Adriano Aguzzi, May Htwe Han, , Annika Keller

This study shows that pericytes restrict immune cell entry into the CNS by maintaining immune quiescence of brain endothelial cells, and their deficiency leads to increased leukocyte infiltration and severe neuroinflammation.

Proceedings of the National Academy of Sciences · Mar 2, 2021Peer-reviewedNeuroscience

Microglia control small vessel calcification via TREM2

Yvette Zarb, Sucheta Sridhar, Sina Nassiri, Sebastian Guido Utz, Johanna Schaffenrath, Upasana Maheshwari, Elisabeth Jane Rushing, K. Peter R. Nilsson, Mauro Delorenzi, Marco Colonna, Melanie Greter, Annika Keller

This study shows microglia control vessel calcification via TREM2, with ablation worsening calcification and revealing a new role in preventing ectopic calcification.

bioRxiv · Nov 5, 2019Neuroscience