K. Peter R. Nilsson

The paper investigates how ischemic injury affects microglial response to Aβ pathology, finding a protective microglial phenotype that promotes benign Aβ plaque formation.

This paper maps α-synuclein pathology and dopaminergic degeneration in mice using multimodal imaging and microscopy, showing spread along the nigrostriatal pathway and microstructural changes.

This study shows synthetic alpha-synuclein fibrils can replicate in mice, causing MSA-like pathology and forming glial cytoplasmic inclusions.

This study examines the diversity of Abeta aggregates in Drosophila models of Alzheimer's disease, showing different aggregate types lead to distinct pathological effects.

This paper compares Aβ fibril structures in three mouse models of Alzheimer's disease, finding age-dependent differences in plaque morphology and polymorph maturation.

The paper uses real-time imaging to show increased mitochondrial oxidative stress in neurons near Aβ plaques in a mouse model of Alzheimer's disease, and demonstrates that this stress can be reduced by targeting calcium influx or using antioxidants.

This paper shows that ASC controls AA amyloidosis by interacting with SAA and that anti-ASC antibodies reduce amyloid loads in mice.

This study uses longitudinal whole-brain imaging to show that anti-Aβ therapies have distinct spatial and temporal efficacies, with polythiophenes showing strong Aβ clearance.

The paper tests if inhibiting the mitochondrial pyruvate carrier reduces synucleinopathy in PD models but finds no effect on Syn aggregation or neurodegeneration.

This study detects cerebral tauopathy in P301L mice using large-field multifocal illumination fluorescence microscopy and a fluorescent ligand, showing increased probe retention in affected mice.

The paper introduces vMSOT with AOI987 to quantify Aβ deposition in AD mouse models, revealing strain-specific patterns.

This paper introduces a transcranial fluorescence microscopy technique to detect amyloid-beta plaques in mouse models of Alzheimer's disease at single-plaque resolution across the entire brain.

This study shows microglia control vessel calcification via TREM2, with ablation worsening calcification and revealing a new role in preventing ectopic calcification.