Author

Peixun Han

RIKENORCID 0000-0001-7632-1634Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 4

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Approach:experimental assay· 3 Organism:zebrafish· 3 Assay:bulk RNA-seq· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1 Assay:protein sequence· 1

Frequent Co-Authors

Shintaro IwasakiiD· 4 shared Yuichiro MishimaiD· 3 shared Kota IshibashiiD· 2 shared Mari MitoiD· 2 shared Seisuke KimuraiD· 2 shared Toshifumi InadaiD· 2 shared Yuichi ShichinoiD· 2 shared Akira YamashitaiD· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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4 shared papersMolecular Biology

Shintaro IwasakiORCID

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4 papers

Recent·Most cited

Molecular BiologybioRxivPreprintSep 1, 2024

Sense codon-misassociated eRF1 elicits ribosome stalling and induction of quality control

Peixun Han, Mari Mito, Akira Yamashita…·Shintaro Iwasaki

This study shows that eRF1 transiently binds to UUA sense codons, causing ribosome stalling and triggering quality control mechanisms in human cells.

2 citations

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Molecular BiologybioRxivPreprintJul 10, 2023

Translation of zinc finger domains induces ribosome collision and Znf598-dependent mRNA decay in vertebrates

Kota Ishibashi, Yuichi Shichino, Peixun Han…·Yuichiro Mishima

The paper investigates how Znf598-mediated no-go decay (NGD) degrades mRNAs encoding C2H2-ZF domains during zebrafish development, preventing ribosome collisions and maintaining translational homeostasis.

DOI 10.1101/2023.07.10.548350

zebrafishbulk RNA-seq

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Molecular BiologyThe EMBO JournalPeer-reviewedJan 18, 2022

Transient ribosome slowdown at the decoding step triggers mRNA degradation independent of Znf598 in zebrafish

Yuichiro Mishima, Peixun Han, Kota Ishibashi…·Shintaro Iwasaki

The paper identifies codon-mediated mRNA decay in zebrafish embryos, showing ribosome decoding kinetics affect mRNA stability independently of Znf598 and stall-dependent decay.

36 citations

zebrafishbulk RNA-seq

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Molecular BiologyCell ReportsPeer-reviewedMay 1, 2020

Genome-wide survey of ribosome collision

Peixun Han, Yuichi Shichino, Tilman Schneider‐Poetsch…·Shintaro Iwasaki

The paper identifies genome-wide ribosome collision sites in humans and zebrafish, revealing their sequence motifs and functional roles in protein synthesis.

187 citationstop 1%

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