Miki Kume

This study shows systemic autoimmunity expands and differentiates microbiota-reactive CD4 T cells, which exacerbate autoimmunity through IL-21 and IFN-gamma mechanisms.

This study shows that TLR7-dependent autoimmunity alters intestinal immune cell dissemination, reducing lymphocytes and increasing myeloid cells, especially dendritic cells, in gut and systemic tissues.

This study shows that downregulation of Sema4A in keratinocytes is associated with non-lesional psoriasis features and that Sema4A regulates skin homeostasis and inflammation.