Author

René Houtman

Alberta Precision LaboratoriesORCID 0000-0001-7639-6310Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Andrew C.B. CatoiD· 1 shared Annick VerheeiD· 1 shared Barbara BellettiiD· 1 shared Christine BlattneriD· 1 shared Christoph W. GrathwoliD· 1 shared Diana MelchersiD· 1 shared Gary R. DavidsoniD· 1 shared Ilenia SegattoiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

Andrew C.B. CatoORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJul 28, 2025

Distinct 2-phenyl-imidazo pyridine derivatives drive ER degradation and selectively impair proliferation of ER+ breast cancer cells via the aryl hydrocarbon receptor

Katrin Koellisch, Christine Blattner, Stefano Motta…·Andrew C.B. Cato

The paper identifies X15695 as an AHR ligand that promotes ER degradation and inhibits ER+ breast cancer cell proliferation more effectively than fulvestrant.

1 citation

humanexperimental assay

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Molecular BiologybioRxivPreprintMay 15, 2023

Antagonism and selective modulation of the human glucocorticoid receptor both reduce recruitment of p300/CBP and the Mediator complex

Laura Van Moortel, Annick Verhee, René Houtman…·Karolien De Bosscher

The paper investigates how different GR ligands affect coregulator recruitment, finding that antagonists and selective modulators reduce interactions with p300/CBP and the Mediator complex compared to full agonists.

2 citations

humanproteomics

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