Systems BiologyJournal of VirologyPeer-reviewed
Understanding hepatitis B virus dynamics and the antiviral effect of interferon-alpha treatment in humanized chimeric mice
Laëtitia Canini, Yuji Ishida, Masataka Tsuge…·Harel Dahari
The paper models HBV kinetics in humanized mice treated with interferon-alpha, lamivudine, or both, revealing biphasic viral decline and distinct treatment effects on HBV DNA synthesis.
28 citations