Author

Lois E. H. Smith

Boston Children's HospitalORCID 0000-0001-7644-6410Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:statistical model· 1

Frequent Co-Authors

Zhongjie FuiD· 2 shared Adam Daniels· 1 shared Andrew KuoiD· 1 shared Antonio ChecaiD· 1 shared Apolonia GardneriD· 1 shared Bongnam JungiD· 1 shared Colin NiaudetiD· 1 shared Constance L. CepkoiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCell Biology

Zhongjie FuORCID

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2 papers

Recent·Most cited

Cell BiologyProceedings of the National Academy of SciencesPeer-reviewedAug 11, 2026

AAV-NRF2 protects retinal and choroidal vasculature in a GDF15-dependent manner in an oxidative damage model of AMD

Shuai Wang, Sophia Zhao, Adam Daniels…·Constance L. Cepko

This study shows that AAV-NRF2 protects retinal and choroidal vasculature in an oxidative damage model of AMD through GDF15, reducing inflammation and oxidative stress.

1 citationtop 3%

mousebulk RNA-seq

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Developmental BiologyeLifePeer-reviewedOct 5, 2022

Endothelial-derived sphingolipids are required for vascular development and systemic lipid homeostasis

Andrew Kuo, Antonio Checa, Colin Niaudet…·Timothy Hla

This study shows that endothelial-derived sphingolipids are essential for vascular development and systemic lipid homeostasis, with effects on retinal vascularization and liver toxicity.

19 citations

mouseexperimental assay

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