Author

Melissa C. Orenduff

Duke UniversityORCID 0000-0001-7652-073XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 2 Physiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:differential expression· 2 Assay:DNA methylation· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:database / resource· 1 Assay:multiome· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Kim M. HuffmaniD· 3 shared Virginia B. KrausiD· 3 shared William E. KrausiD· 3 shared Carl F. PieperiD· 2 shared Daniel W. BelskyiD· 2 shared David L. CorcoraniD· 2 shared Michael Steffen KoboriD· 2 shared Abner T. ApsleyiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersGenomics

Kim M. HuffmanORCID

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3 papers

Recent·Most cited

Regulation of Small RNAs by Exercise and Their Role in Insulin Sensitivity

Christopher G. Vann, Akshay Bareja, Monica J. Hubal, Syeda Iffat Naz, Sisi Ma, Melissa C. Orenduff, Leanna M. Ross, William C Bennett, Kim M. Huffman, Constantin Aliferis, William E. Kraus, Virginia B. Kraus

This study examines how aerobic exercise affects small RNA expression in skeletal muscle and plasma, linking changes to improved insulin sensitivity.

bioRxiv · May 17, 2026 · PreprintPhysiology

The CALERIE™ Genomic Data Resource

Calen Patrick Ryan, David L. Corcoran, Nirad Banskota, Claire Eckstein Indik, Aris Floratos, Richard A. Friedman, Michael Steffen Kobor, Virginia B. Kraus, William E. Kraus, Julia L. MacIsaac, Melissa C. Orenduff, Carl F. Pieper, James P. White, Luigi Ferrucci, Steve Horvath, , Daniel W. Belsky

The paper presents a genomic data resource from a caloric restriction trial, including SNP genotypes and multi-omic longitudinal data from multiple tissues.

Nature Aging · Dec 13, 2024Peer-reviewedGenomics

Epigenome-wide association study analysis of calorie restriction in humans, CALERIE™ Trial analysis

Megan E. Ramaker, David L. Corcoran, Abner T. Apsley, Michael Steffen Kobor, Virginia B. Kraus, William E. Kraus, David T S Lin, Melissa C. Orenduff, Carl F. Pieper, Reem Waziry, Kim M. Huffman, Daniel W. Belsky

This study analyzes DNA methylation changes in humans undergoing calorie restriction, finding CR-induced DNAm changes opposite BMI and smoking associations and aligned with aging-related CpG sites.

bioRxiv · Jun 3, 2022 · PreprintGenomics