Biomaterial Scaffold Stiffness Influences the Foreign Body Reaction, Tissue Stiffness, Angiogenesis and Neuroregeneration in Spinal Cord Injury
Yifeng Zheng, Maximilian Nützl, Thomas Schackel…·Radhika Puttagunta
Author
University Hospital HeidelbergORCID 0000-0001-7674-8064Unclaimed ORCID profile · follow to get notified of new preprints
6 papers
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Yifeng Zheng, Maximilian Nützl, Thomas Schackel…·Radhika Puttagunta
Christopher Sliwinski, Laura Heutehaus, Francisco José Taberner…·Radhika Puttagunta
This study investigates the role of mechanoreceptors and nociceptors in spinal cord injury-induced neuropathic pain, finding that early mechanoreceptor ablation reduces pain behavior, while nociceptor hyperexcitability and sprouting are key drivers of pain.
Naëmi Kuehn, Andreas Schwarz, Carlo A. Beretta…·Radhika Puttagunta
This study shows that damaging intermediate gray matter in the lumbar spinal cord of rats causes long-term locomotor deficits, with machine learning confirming the link to interneuronal loss.
Guiping Kong, Luming Zhou, Elisabeth Serger…·Simone Di Giovanni
Arnau Hervera, Luming Zhou, Ilaria Palmisano…·Simone Di Giovanni
The paper identifies PP4-dependent HDAC3 dephosphorylation as a mechanism distinguishing axonal regeneration from regenerative failure in nerve injuries.
Wilson Pak-Kin Lou, Álvaro Mateos, Marta Koch…·Ana Martín-Villalba
This study identifies post-transcriptional regulation by Cpeb1 as a mechanism enhancing CNS axonal regeneration in mice and Drosophila.