Operation of a TCA cycle subnetwork in the mammalian nucleus
Eleni Kafkia, Amparo Andrés‐Pons, Kerstin Ganter, Markus Seiler, Tom S. Smith, Anna Andrejeva, Paula Jouhten, Filipa M. Pereira, Catarina de Matos Ferraz Franco, Anna Kuroshchenkova, Sergio Leone, Ritwick Sawarkar, Rebecca H. Boston, James E. D. Thaventhiran, Judith B. Zaugg, , Kiran Raosaheb Patil
The paper shows that parts of the TCA cycle operate in the nucleus, challenging the canonical view of metabolic compartmentalization.
Science Advances · Aug 31, 2022Peer-reviewedSystems Biology