Markus Seiler

This study identifies a nucleolar role for Drosophila Argonaute 1, showing it associates with snoRNP machinery and regulates pre-rRNA levels and cell growth.

The paper shows that CLB2 mRNA localization to the bud via the She2/She3 complex enhances translation, linking cell growth to cell cycle progression through a ZIP-code element in the coding sequence.

The paper identifies a consensus motif for She2p/3p recognition sites in yeast RNA, showing that spatial arrangement of sequence features is more important than sequence order for function.

The paper shows that parts of the TCA cycle operate in the nucleus, challenging the canonical view of metabolic compartmentalization.