Satyanarayan Rao

This study shows endosulfan disrupts Hedgehog signaling by altering GSK3β activity, leading to ciliopathy-like effects in mice and linking to human reproductive disorders.

This study shows endosulfan, a pesticide, suppresses hedgehog signaling by activating GSK3β and repressing GLI-regulated genes, mimicking genetic ciliopathies.

This paper identifies a novel bacteriophage endolysin LysPH with broad antibacterial activity and elucidates its structural basis for substrate recognition and catalytic activation.

SMTrackR is a Bioconductor package for visualizing and quantifying protein-DNA binding states on single-molecule sequencing data.

The paper shows that estradiol concentration changes the chromatin binding sites of the estrogen receptor, affecting its localization and interaction with DNA motifs.

This paper maps transcription factor-nucleosome dynamics from plasma cfDNA to identify cancer states and tissue-of-origin.

The paper characterizes TF cooperativity at active enhancers in Drosophila using nuclease footprinting and chromatin profiling, finding that cooperativity is common and facilitates enhancer function.